Keppra is an anticonvulsant medication that the chemical composition is different from other similar tools for action. The active substance medications - levetiracetam, the effect of which is not known until the end, but found that synaptic transmission (propagation of nerve impulses), it does not break.
The efficacy of Keppra drug in focal epilepsy, as well as its more serious stages, such as paroxysmal reaction epileptiform manifestations. Judging by the reviews of Keppra, the patient's condition has stabilized after two days if you take the drug twice a day.
Release form of the drug Keppra
Keppra - coated tablets are packaged in foil blisters in a cardboard box; Dosage of:
- 250 mg.
- 500 mg.
- 1000 mg.
The drug Keppra is effective in the treatment of children over 16 years of age, adults with epilepsy who have observed partial seizures - seizures, which are accompanied by autonomic, sensory, motor, mental disorders.
Good reviews of Keppra, which is not used as a standalone tool, and include comprehensive treatment of partial seizures in adults and children over the age of 4 years (Keppra tablets) and children older than one month (solution Keppra).
Besides Keppra can be used for treating tonic-clonic seizures in adolescents over 12 years of age, adults suffering from idiopathic generalized epilepsy, myoclonic seizures in the same age group of patients with juvenile myoclonic epilepsy.
Keppra can cause headache, diarrhea, asthenia, nausea, seizures, aggression, nervousness, tremor, dizziness, drowsiness, appetite loss, lability, diplopia, skin rash, tremors.
In case of overdose the stomach is washed, if necessary, carry out hemodialysis, symptomatic therapy.
Terms and Conditions of storage
Tablets Keppra should be stored in a dry place at temperatures not above 25 ° C. Shelf life - 3 years. The solution for the reception should be stored inside in a dark place at a temperature no higher than 30 ° C. Shelf life - 3 years.
Epilepsy is a condition characterized by repeated (more than two) epileptic seizures not provoked by any immediately identifiable causes. An epileptic attack is a clinical manifestation of an abnormal and excessive discharge of neurons in the brain causing sudden transient pathological phenomena (sensory, motor, mental, vegetative symptoms, changes in consciousness). It should be remembered that several provoked or conditioned by any clear reasons (brain tumor, TBI) epileptic seizures do not indicate the patient has epilepsy.
Classification of epileptic seizures
According to the international classification of epileptic seizures, partial (local, focal) forms and generalized epilepsy are isolated. Attacks of focal epilepsy are divided into: simple (without disorders of consciousness) - with motor, somatosensory, vegetative and psychic symptoms and complicated - accompanied by a violation of consciousness. Primary-generalized seizures occur with involvement in the pathological process of both hemispheres of the brain. Types of generalized seizures: myoclonic, clonic, absences, atypical absences, tonic, tonic-clonic, atonic.
There are unclassified epileptic seizures - not suited to any of the above described types of seizures, and also some neonatal seizures (chewing movements, rhythmic eye movements). There are also repeated epileptic seizures (provoked, cyclical, accidental) and prolonged seizures (epileptic status).
Treatment of epilepsy
All methods of treatment of epilepsy are aimed at stopping seizures, improving the quality of life and stopping medication (at the stage of remission). In 70% of cases, adequate and timely treatment leads to the cessation of epileptic seizures. Before appointing antiepileptic drugs, a detailed clinical examination should be performed, and the results of MRI and EEG should be analyzed. The patient and his family should be informed not only about the rules for taking medications, but also about possible side effects. Indications for hospitalization are: for the first time in life a developed epileptic attack, epileptic status and the need for surgical treatment of epilepsy.
One of the principles of drug treatment of epilepsy is monotherapy. The drug is prescribed in a minimal dose with a subsequent increase in it until the seizures stop. In case of insufficiency of the dose, it is necessary to check the regularity of taking the drug and to find out if the maximum tolerated dose has been achieved. The use of most antiepileptic drugs requires constant monitoring of their concentration in the blood. Treatment with pregabalin, levetiracetam, valproic acid begins with a clinically effective dose, with the appointment of lamotrigine, topiramate, carbamazepine, slow titration of the dose is necessary.
Treatment of newly diagnosed epilepsy begins with both traditional (carbamazepine and valproic acid) and with the latest antiepileptic drugs (topiramate, oxcarbazepine, levetiracetam) registered for monotherapy. When choosing between traditional and newer drugs, it is necessary to take into account the individual characteristics of the patient (age, sex, concomitant pathology). To treat unidentified seizures of epilepsy, valproic acid is used. When prescribing a particular antiepileptic drug should strive for the minimum possible frequency of its reception (up to 2 times / day). Due to the stable concentration in the plasma, sustained-release drugs are more effective. The dose of the drug prescribed to an elderly patient creates a higher concentration in the blood than a similar dose of the drug prescribed to a young patient, so it is necessary to start treatment with small doses and then titrate them. The withdrawal of the drug is carried out gradually, taking into account the form of epilepsy, its prognosis and the possibility of resuming seizures.
Pharmacoresistant epilepsies (continued seizures, inefficiency of adequate antiepileptic treatment) require additional examination of the patient to decide on the question of surgical treatment. Preoperative examination should include video EEG recording of seizures, obtaining reliable data on localization, anatomical features and the nature of the spread of the epileptogenic zone (MRI). Based on the results of the above studies, the nature of surgical intervention is determined: surgical removal of epileptogenic brain tissue (cortical topotomy, lobectomy, hemisferectomy, multilobectomy); Selective surgery (amygdalo-hippocampectomy with temporal epilepsy); Kallozotomy and functional stereotaxic interference; Vagus stimulation.
There are strict indications for each of the above surgical procedures. They can only be carried out in specialized neurosurgical clinics that have the appropriate equipment, and with the participation of highly qualified specialists (neurosurgeons, neuro-radiologists, neuropsychologists, neurophysiologists, etc.)
Prophylaxis of epilepsy
Prevention of epilepsy involves the possible prevention of TBI, intoxications and infectious diseases, the prevention of possible marriages between patients with epilepsy, adequate temperature reduction in children to prevent fever, the consequence of which may be epilepsy.
Your questions and suggestions
Hello, prompt, please, the drug is released from Keppra pharmacies sure if the recipe? Do OTC these drugs?
Tell me - is it possible to dissolve the pill in water before baby reception, if he can not swallow whole or crush it better? We are talking about Keppra. If you can be dissolved, how long drugs do not lose their properties in water (because they are not dissolved immediately). Thank you.
Hello! Please tell us whether there is a practice-treatment of a child (age 4 months) drug Keppra? Thank you bye!
Please tell me if you have any keppra analogs or drugs can still be used for epilepsy?
Is it true that after taking the drug Keppra, during the detection of neurological symptoms undesirable side driving, works associated with danger ???
We were transferred from Depakin to Keppra, because the seizures became more frequent and the number of platelets in the blood decreased. On one Keppra lasted almost three months, the drug really liked, did not cause side effects, the EEG began to improve, there were no seizures.
Today we returned from the professor. Looked at our EEG. Against Keppra's background there is no convulsive readiness. This is a very good result for two months of taking the drug. It is strongly recommended to continue to be friends with this drug from six months to a year, it is better to take within a year, along the way to do control EEG. That's such good news we have. Keppru take 250 mg per day (1/2 in the morning, 1/2 in the eveni.