Pregnancy and epilepsy
Pregnancy and epilepsy In some cases, pregnancy does not change the frequency of seizures, and sometimes even improves the control of seizures, but in about 1/3 of cases there is a deterioration in the control of seizures during pregnancy. This may be due to a number of factors. High levels of estrogen/progesterone may play a role in the first trimester of pregnancy. In addition, there is a decrease in the level of some AEP in plasma due to physiological processes occurring during pregnancy. In 2 and 3 trimesters of pregnancy, the volume of blood plasma increases by about 1/3, thereby reducing the concentration of AEP when administered in the body of the previous dose. Changes in AEP concentrations are also explained by an increase in the rate of excretion of…